Miniaturization refers to that process which leads to the shortening of length and breadth of hair due to the action of androgens.
Observe the two pictures below. The first one represents a photo of a normal scalp in which the follicular units are healthy and thick. Their shafts are equally thick. Whereas the photo to the right depicts a condition where the hair are not uniform in their diameters and have miniaturized due to androgenetic alopecia.
Thyroid disease and anemia in men are known to lead to diffuse hair loss in men. Also some medications which control high blood pressure and depression are also known to cause hair loss in men.
Detecting diffuse hair loss, which may not be caused due to androgenetic factors, becomes easy when tests for lupus and syphilis are conducted.
If androgenetic alopecia can’t be diagnosed, further information for the ongoing condition may be obtained through a hair-pull test, by obtaining a scraping and culture of fungus present in hair follicles, a microscopic examination of the hair shaft and its bulb, and by performing a scalp biopsy. It’s essential that a dermatologic inspection of the scalp is conducted whenever the reasons for hair loss are unclear.
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